Pattern of salivary gland tumors in Manipur, India: A 10 year study

Rajesh Singh Laishram; Arun Kumar K.; Gayatri Devi Pukhrambam; Sharmila Laishram; Kaushik Debnath

doi:10.4103/2278-330x.119886

View/Download PDF

Buy Reprints

PDF

Translate this page into:

THROUGH THE MICROSCOPE: Original Article

02 (

); 250-253

doi:

10.4103/2278-330x.119886

Pattern of salivary gland tumors in Manipur, India: A 10 year study

Rajesh Singh Laishram^1,, Arun Kumar K.¹, Gayatri Devi Pukhrambam¹, Sharmila Laishram¹, Kaushik Debnath¹

1 Department of Pathology, Regional Institute of Medical Sciences, Lamphelpat, Imphal, Manipur, India

*Corresponding author: Dr. Rajesh Singh Laishram. rajeshlaishr@gmail.com

Published: 2020-12-31

MedIntel Services Pvt Ltd. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

Licence

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

Disclaimer:
This article was originally published by Thieme Medical and Scientific Publishers Pvt. Ltd. and was migrated to Scientific Scholar after the change of Publisher.

Abstract

Background: Salivary gland lesions, especially the neoplastic lesions constitute a highly heterogeneous histopathologic group. Several studies have reported a significant difference in the global distribution of salivary gland tumors, but no formal study has been carried out in this part of the globe. Objectives: To document the pattern of various salivary gland tumors in Manipur, a state in North Eastern India. Materials and Methods: This is a 10 years (2002-2011) retrospective study of all salivary gland specimens received at our referral teaching hospital in Manipur, India. All the histopathology slides of salivary gland specimens during the study period were reviewed and clinical details were obtained from the archives. Restaining of slides and fresh sections of tissue blocks were performed whenever required. Data thus collected were analyzed. Results: A total of 104 cases of salivary gland lesions were studied during the study period. Age ranged from 5 years to 78 years with an overall slight female preponderance (M:F = 1:1.08). Parotid (56.65%) was the commonest gland involved followed by submandibular gland (31.73%). Neoplastic lesions comprised of 78 (75%) cases and non-neoplastic lesions constituted 25% (26 cases). Among the neoplastic lesions, benign lesions (53.85%) predominated over malignant lesions (21.15%). Pleomorphic adenoma was the commonest benign neoplastic lesion and mucoepidermoid carcinoma was the commonest malignant tumor. Chronic sialadenitis was the predominant lesion in the non-neoplastic group. Conclusion: The principal site for salivary gland tumors was the parotid gland and pleomorphic adenoma outnumbered all the other tumors. Females are more affected in the malignant group.

Keywords

References

Ezeanolue BC. Salivary gland neoplasms: A descriptive analysis of the pattern seen in Enugu. West Afr J Med 1999;18:179-82.
Odukoya O. Pleomorphic adenoma of salivary glands in Lagos, Nigeria. Afr J Med Sci 1990;19:195-9.
Vuhahula EA. Salivary gland tumors in Uganda: Clinical pathological study. Afr Health Sci 2004;4:15-23.
Nepal A, Chettri ST, Joshi RR, Bhattarai M, Ghimire A, Karki S. Primary salivary gland tumors in eastern Nepal tertiary care hospital. J Nepal Health Res Counc 2010;8:31-4.
National cancer Registry programme. Annual report of Population based cancer registry, Imphal, ManipurState. Indian Counc Med Res 2009:33-4.
Eveson JW, Cawson RA. Salivary gland tumours. A review of 2410 cases with particular reference to histological types, site, age and sex distribution. J Pathol 1985;146:51-8.
Arotiba GT. Salivary gland neoplasms in Lagos, Nigeria. West Afr J Med 1996;15:11-7.
Ma′aita JK, Al-Kaisi N, Al-Tamimi S, Wraikat A. Salivary gland tumors in Jordan: A retrospective study of 221 patients. Croat Med J 1999;40:539-42.
Vargas PA, Gerhard R, AraújoFilho VJ, de Castro IV. Salivary gland tumors in a Brazilian population: A retrospective study of 124 cases. Rev Hosp Clin Fac Med Sao Paulo 2002;57:271-6.
Satko I, Stanko P, Longauerová I. Salivary gland tumours treated in the stomatological clinics in Bratislava. J Craniomaxillofac Surg 2000;28:56-61.
Ahmad S, Lateef M, Ahmad R. Clinicopathological study of primary salivary gland tumours in Kashmir. JK Pract 2002;9:231-3.
Ochicha O, Malami S, Mohammed A, Atanda A. A histopathologic study of salivary gland tumors in Kano, northern Nigeria. Indian J Pathol Microbiol 2009;52:473-6.
Loyola AM, de Araújo VC, de Sousa SO, de Araújo NS. Minor salivary gland tumours. A retrospective study of 164 cases in a Brazilian population. Eur J Cancer B Oral Oncol 1995;31B:197-201.
Rivera-Bastidas H, Ocanto RA, Acevedo AM. Intraoral minor salivary gland tumors: A retrospective study of 62 cases in a Venezuelan population. J Oral Pathol Med 1996;25:1-4.
Ito FA, Ito K, Vargas PA, de Almeida OP, Lopes MA. Salivary gland tumors in a Brazilian population: A retrospective study of 496 cases. Int J Oral Maxillofac Surg 2005;34:533-6.
Frade Gonzalez C, Lozano Ramirez A, Garcia Caballero T, Labella Caballero T. Epidemiological study of salivary gland tumours. Rev Laryngol Otol Rhinol (Bord) 1999;120:331-6.
Li LJ, Li Y, Wen YM, Liu H, Zhao HW. Clinical analysis of salivary gland tumor cases in West China in past 50 years. Oral Oncol 2008;44:187-92.
Toida M, Shimokawa K, Makita H, Kato K, Kobayashi A, Kusunoki Y, et al. Intraoral minor salivary gland tumors: A clinicopathological study of 82 cases. Int J Oral Maxillofac Surg 2005;34:528-32.
Lopes MA, Kowalski LP, da Cunha Santos G, Paes de Almeida O. A clinicopathologic study of 196 intraoral minor salivary gland tumours. J Oral Pathol Med 1999;28:264-7.
Chung YF, Khoo ML, Heng MK, Hong GS, Soo KC. Epidemiology of Warthin′s tumour of the parotid gland in an Asian population. Br J Surg 1999;86:661-4.
Eveson JW, Cawson RA. Warthin′s tumor (cystadenolymphoma) of salivary glands. A clinicopathologic investigation of 278 cases. Oral Surg Oral Med Oral Pathol 1986;61:256-62.
Pinkston JA, Cole P. Incidence rates of salivary gland tumors: Results from a population-based study. Otolaryngol Head Neck Surg 1999;120:834-40.
Batsakis JG, Regezi JA. The pathology of head and neck tumors: Salivary glands, part 1. Head Neck Surg 1978;1:59-68.

Fulltext Views
38

PDF downloads
10

View/Download PDF
Download Citations

BibTeX
RIS

Show Sections

[1] Ezeanolue BC. Salivary gland neoplasms: A descriptive analysis of the pattern seen in Enugu. West Afr J Med 1999;18:179-82.

[2] Odukoya O. Pleomorphic adenoma of salivary glands in Lagos, Nigeria. Afr J Med Sci 1990;19:195-9.

[3] Vuhahula EA. Salivary gland tumors in Uganda: Clinical pathological study. Afr Health Sci 2004;4:15-23.

[4] Nepal A, Chettri ST, Joshi RR, Bhattarai M, Ghimire A, Karki S. Primary salivary gland tumors in eastern Nepal tertiary care hospital. J Nepal Health Res Counc 2010;8:31-4.

[5] National cancer Registry programme. Annual report of Population based cancer registry, Imphal, ManipurState. Indian Counc Med Res 2009:33-4.

[6] Eveson JW, Cawson RA. Salivary gland tumours. A review of 2410 cases with particular reference to histological types, site, age and sex distribution. J Pathol 1985;146:51-8.

[7] Arotiba GT. Salivary gland neoplasms in Lagos, Nigeria. West Afr J Med 1996;15:11-7.

[8] Ma′aita JK, Al-Kaisi N, Al-Tamimi S, Wraikat A. Salivary gland tumors in Jordan: A retrospective study of 221 patients. Croat Med J 1999;40:539-42.

[9] Vargas PA, Gerhard R, AraújoFilho VJ, de Castro IV. Salivary gland tumors in a Brazilian population: A retrospective study of 124 cases. Rev Hosp Clin Fac Med Sao Paulo 2002;57:271-6.

[10] Satko I, Stanko P, Longauerová I. Salivary gland tumours treated in the stomatological clinics in Bratislava. J Craniomaxillofac Surg 2000;28:56-61.

[11] Ahmad S, Lateef M, Ahmad R. Clinicopathological study of primary salivary gland tumours in Kashmir. JK Pract 2002;9:231-3.

[12] Ochicha O, Malami S, Mohammed A, Atanda A. A histopathologic study of salivary gland tumors in Kano, northern Nigeria. Indian J Pathol Microbiol 2009;52:473-6.

[13] Loyola AM, de Araújo VC, de Sousa SO, de Araújo NS. Minor salivary gland tumours. A retrospective study of 164 cases in a Brazilian population. Eur J Cancer B Oral Oncol 1995;31B:197-201.

[14] Rivera-Bastidas H, Ocanto RA, Acevedo AM. Intraoral minor salivary gland tumors: A retrospective study of 62 cases in a Venezuelan population. J Oral Pathol Med 1996;25:1-4.

[15] Ito FA, Ito K, Vargas PA, de Almeida OP, Lopes MA. Salivary gland tumors in a Brazilian population: A retrospective study of 496 cases. Int J Oral Maxillofac Surg 2005;34:533-6.

[16] Frade Gonzalez C, Lozano Ramirez A, Garcia Caballero T, Labella Caballero T. Epidemiological study of salivary gland tumours. Rev Laryngol Otol Rhinol (Bord) 1999;120:331-6.

[17] Li LJ, Li Y, Wen YM, Liu H, Zhao HW. Clinical analysis of salivary gland tumor cases in West China in past 50 years. Oral Oncol 2008;44:187-92.

[18] Toida M, Shimokawa K, Makita H, Kato K, Kobayashi A, Kusunoki Y, et al. Intraoral minor salivary gland tumors: A clinicopathological study of 82 cases. Int J Oral Maxillofac Surg 2005;34:528-32.

[19] Lopes MA, Kowalski LP, da Cunha Santos G, Paes de Almeida O. A clinicopathologic study of 196 intraoral minor salivary gland tumours. J Oral Pathol Med 1999;28:264-7.

[20] Chung YF, Khoo ML, Heng MK, Hong GS, Soo KC. Epidemiology of Warthin′s tumour of the parotid gland in an Asian population. Br J Surg 1999;86:661-4.

[21] Eveson JW, Cawson RA. Warthin′s tumor (cystadenolymphoma) of salivary glands. A clinicopathologic investigation of 278 cases. Oral Surg Oral Med Oral Pathol 1986;61:256-62.

[22] Pinkston JA, Cole P. Incidence rates of salivary gland tumors: Results from a population-based study. Otolaryngol Head Neck Surg 1999;120:834-40.

[23] Batsakis JG, Regezi JA. The pathology of head and neck tumors: Salivary glands, part 1. Head Neck Surg 1978;1:59-68.

Pattern of salivary gland tumors in Manipur, India: A 10 year study

Abstract

Abstract

Keywords

References

Suggested read for related articles:

We value your privacy