A retrospective study of clinico-pathological spectrum of carcinoma breast
in a West Delhi, India

Jitendra Singh Nigam; Poonam Yadav; Neelam Sood

doi:10.4103/2278-330X.136804

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SOUTH ASIAN UPDATE : Original Article

03 (

); 179-181

doi:

10.4103/2278-330X.136804

A retrospective study of clinico-pathological spectrum of carcinoma breast in a West Delhi, India

Jitendra Singh Nigam^1,, Poonam Yadav¹, Neelam Sood¹

1 Department of Pathology, Deen Dayal Upadhyay Hospital, Hari Nagar, New Delhi, India

*Corresponding author: Dr. Jitendra Singh Nigam. nigamjs@gmail.com

Published: 2020-12-31

MedIntel Services Pvt Ltd. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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Abstract

Background: Data on the demographic profile of breast cancer patients from Delhi is scarce and whatever is available is from higher referral center. Our hospital caters to patients from an urban population of the lower socioeconomic strata and is a representation of cases at a tertiary care hospital in west Delhi. In Delhi, breast cancer (26.8%) is commonest cancer among the female followed by cervix (12.5%), gallbladder (7.2%), ovary (7.1%), and uterus (3.3%). Aims and Objectives: A retrospective audit of breast cancer patients presenting at a tertiary referral center from 2004 to 2011. Materials and Methods: A total of 328 cases diagnosed as carcinoma breast on histopathology from year 2004 to 2011 were retrieved and studied retrospectively with regards to demographic profile and their histological features with estrogen receptor (ER), progesterone receptor (PR), and Her2neu status.Results: The median age of presentation was 49 years of age. Infiltrating ductal carcinoma (IDC, not otherwise specified (NOS)) was the commonest histopathological variant (81.40%) followed by medullary carcinoma (10.36%) and mucinous carcinoma (2.74%). Triple negative were found to be the commonest group comprising 39.4% of all the cases followed by ER and PR both positive. Pathological tumor, node, and metastasis (TNM) staging showed most common group was T ₂ N ₀ M _{0 (} 19.5%) followed by T ₂ N ₁ M ₀ (17.1%) and T ₂ N ₂ M ₀ (14%). Conclusion: The incidence of breast cancer in the India and include a higher incidence of ER, PR, and Her2neu negative disease in west Delhi.

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References

WHO Breast Cancer Awareness Month in October. Available from: http://www.who.int/cancer/events/breast_cancer_month/en/index.html [Last accessed on 2013 Dec 29].
Green M, Raina V. Epidemiology, screening and diagnosis of breast cancer in the Asia-Pacific region: Current perspectives and important considerations. Asia Pac J Clin Oncol 2008;4:5-13.
Chauhan A, Subba SH, Menezes RG, Shetty BS, Thakur V, Chabra S, et al. Younger women are affected by breast cancer in south india-a hospital-based descriptive study. Asian Pac J Cancer Prev 2011;12:709-11.
Agarwal G, Pradeep PV, Aggarwal V, Yip CH, Cheung PS. Spectrum of breast cancer in Asian women. World J Surg 2007;31:1031-40.
Shetty P. India faces growing breast cancer epidemic. Lancet 2012;379:992-3.
National Cancer registry Program: Trends over time for all sites and on selected leading sites of cancer. Time trends in cancer incidence rates 1982-2010. New Delhi: Indian Council of Medical Research; 2012. p. 28-30, 83-6. Available from: http://www.ncrpindia.org/ALL_NCRP_REPORTS/TREND_REPORT_1982_2010/ALL_CONTENT/ALL_PDF/Trends_Over_Time_For_All_Sites.pdf [Last accessed on 2014 Mar 03].
Murthy NS, Agarwal UK, Chaudhry K, Saxena S. A study on time trends in incidence of breast cancer -Indian scenario. Eur J Cancer Care (Engl) 2007;16:185-6.
Satyanarayana L, Asthana S. Life time risk for development of ten major cancers in India and its trends over the years 1982 to 2000. Indian J Med Sci 2008;62:35-44.
National Cancer registry Program: Leading sites of cancers. In: Three year report of population based cancer registries: 2009-2011. Indian Council of Medical Research, New Delhi 2012. p- 10. Available from http://www.ncrpindia.org/ALL_NCRP_REPORTS/PBCR_REPORT_2009_2011/ALL_CONTENT/PDF_Printed_Version/Chapter 2_Printed.pdf [Last accessed on 2014 Mar 03].
Saxena S, Rekhi B, Bansal A, Bagga A, Chintamani, Murthy NS. Clinico-morphological patterns of breast cancer including family history in a New Delhi hospital, India--A cross-sectional study. World J Surg Oncol 2005;3:67.
Sandhu DS, Sandhu S, Karwasra RK, Marwah S. Profile of breast cancer patients at a tertiary care hospital in north India. Indian J Cancer 2010;47:16-22.
Pakseresht S, Ingle GK, Bahadur AK, Ramteke VK, Singh MM, Garg S, et al. Risk factors with breast cancer among women in Delhi. Indian J Cancer 2009;46:132-8.
Leong SP, Shen ZZ, Liu TJ, Agarwal G, Tajima T, Paik NS, et al. Is breast cancer the same disease in Asian and Western countries? World J Surg 2010;34:2308-24.
Mathew A, Pandey M, Rajan B. Do younger women with non-metastatic and non-inflammatory breast carcinoma have poor prognosis? World J Surg Oncol 2004;2:2.
Shavers VL, Harlan LC, Stevens JL. Racial/ethnic variation in clinical presentation, treatment, and survival among breast cancer patients under age 35. Cancer 2003;97:134-47.
Wani SQ, Khan T, Wani SY, Koka AH, Arshad S, Rafiq L, et al. Clinicoepidemiological analysis of female breast cancer patients in Kashmir. J Cancer Res Ther 2012;8:389-93.
Meshram II, Hiwarkar PA, Kulkarni PN. Reproductive risk factors for breast cancer: A case control study. Online J Health Allied Sci 2009;8:5.
Gajalakshmi V, Mathew A, Brennan P, Rajan B, Kanimozhi VC, Mathews A, et al. Breastfeeding and breast cancer risk in India: A multicenter case-control study. Int J Cancer 2009;125:662-5.
National Cancer registry Program: Ten year consolidated report of the Hospital Based Cancer Registries, 1984-1993. An assessment of the burden and care of cancer patients. New Delhi: Indian Council of Medical Research; 2001.
Kakarala M, Rozek L, Cote M, Liyanage S, Brenner DE. Breast cancer histology and receptor status characterization in Asian Indian and Pakistani women in the U.S.--a SEER analysis. BMC Cancer 2010;10:191.

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[1] WHO Breast Cancer Awareness Month in October. Available from: http://www.who.int/cancer/events/breast_cancer_month/en/index.html [Last accessed on 2013 Dec 29].

[2] Green M, Raina V. Epidemiology, screening and diagnosis of breast cancer in the Asia-Pacific region: Current perspectives and important considerations. Asia Pac J Clin Oncol 2008;4:5-13.

[3] Chauhan A, Subba SH, Menezes RG, Shetty BS, Thakur V, Chabra S, et al. Younger women are affected by breast cancer in south india-a hospital-based descriptive study. Asian Pac J Cancer Prev 2011;12:709-11.

[4] Agarwal G, Pradeep PV, Aggarwal V, Yip CH, Cheung PS. Spectrum of breast cancer in Asian women. World J Surg 2007;31:1031-40.

[5] Shetty P. India faces growing breast cancer epidemic. Lancet 2012;379:992-3.

[6] National Cancer registry Program: Trends over time for all sites and on selected leading sites of cancer. Time trends in cancer incidence rates 1982-2010. New Delhi: Indian Council of Medical Research; 2012. p. 28-30, 83-6. Available from: http://www.ncrpindia.org/ALL_NCRP_REPORTS/TREND_REPORT_1982_2010/ALL_CONTENT/ALL_PDF/Trends_Over_Time_For_All_Sites.pdf [Last accessed on 2014 Mar 03].

[7] Murthy NS, Agarwal UK, Chaudhry K, Saxena S. A study on time trends in incidence of breast cancer -Indian scenario. Eur J Cancer Care (Engl) 2007;16:185-6.

[8] Satyanarayana L, Asthana S. Life time risk for development of ten major cancers in India and its trends over the years 1982 to 2000. Indian J Med Sci 2008;62:35-44.

[9] National Cancer registry Program: Leading sites of cancers. In: Three year report of population based cancer registries: 2009-2011. Indian Council of Medical Research, New Delhi 2012. p- 10. Available from http://www.ncrpindia.org/ALL_NCRP_REPORTS/PBCR_REPORT_2009_2011/ALL_CONTENT/PDF_Printed_Version/Chapter 2_Printed.pdf [Last accessed on 2014 Mar 03].

[10] Saxena S, Rekhi B, Bansal A, Bagga A, Chintamani, Murthy NS. Clinico-morphological patterns of breast cancer including family history in a New Delhi hospital, India--A cross-sectional study. World J Surg Oncol 2005;3:67.

[11] Sandhu DS, Sandhu S, Karwasra RK, Marwah S. Profile of breast cancer patients at a tertiary care hospital in north India. Indian J Cancer 2010;47:16-22.

[12] Pakseresht S, Ingle GK, Bahadur AK, Ramteke VK, Singh MM, Garg S, et al. Risk factors with breast cancer among women in Delhi. Indian J Cancer 2009;46:132-8.

[13] Leong SP, Shen ZZ, Liu TJ, Agarwal G, Tajima T, Paik NS, et al. Is breast cancer the same disease in Asian and Western countries? World J Surg 2010;34:2308-24.

[14] Mathew A, Pandey M, Rajan B. Do younger women with non-metastatic and non-inflammatory breast carcinoma have poor prognosis? World J Surg Oncol 2004;2:2.

[15] Shavers VL, Harlan LC, Stevens JL. Racial/ethnic variation in clinical presentation, treatment, and survival among breast cancer patients under age 35. Cancer 2003;97:134-47.

[16] Wani SQ, Khan T, Wani SY, Koka AH, Arshad S, Rafiq L, et al. Clinicoepidemiological analysis of female breast cancer patients in Kashmir. J Cancer Res Ther 2012;8:389-93.

[17] Meshram II, Hiwarkar PA, Kulkarni PN. Reproductive risk factors for breast cancer: A case control study. Online J Health Allied Sci 2009;8:5.

[18] Gajalakshmi V, Mathew A, Brennan P, Rajan B, Kanimozhi VC, Mathews A, et al. Breastfeeding and breast cancer risk in India: A multicenter case-control study. Int J Cancer 2009;125:662-5.

[19] National Cancer registry Program: Ten year consolidated report of the Hospital Based Cancer Registries, 1984-1993. An assessment of the burden and care of cancer patients. New Delhi: Indian Council of Medical Research; 2001.

[20] Kakarala M, Rozek L, Cote M, Liyanage S, Brenner DE. Breast cancer histology and receptor status characterization in Asian Indian and Pakistani women in the U.S.--a SEER analysis. BMC Cancer 2010;10:191.

A retrospective study of clinico-pathological spectrum of carcinoma breast in a West Delhi, India

Abstract

Abstract

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References

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