South Asian Journal of Cancer

ORIGINAL ARTICLE: BREAST CANCER
Year
: 2017  |  Volume : 6  |  Issue : 2  |  Page : 47--50

Efficacy and safety of short course adjuvant trastuzumab combination chemotherapy in breast cancer


Sachin S Hingmire1, Mahesh B Sambhus1, Dhananjay S Kelkar1, Sujit Joshi1, Purvish M Parikh2, R Bharath3 
1 Department of Oncology, Deenanath Mangeshkar Hospital and Research Centre, Pune, India
2 Department of Oncology, Asian Institute of Oncology, Mumbai, Maharashtra, India
3 Department of Oncology, Kovai Medical Centre and Hospital, Coimbatore, Tamil Nadu, India

Correspondence Address:
Sachin S Hingmire
Department of Oncology, Deenanath Mangeshkar Hospital and Research Centre, Pune
India

Background: The adjuvant short course 9-week trastuzumab combination therapy for human epidermal receptor 2 positive breast cancer patients may often be considered as a cost-effective and safe option and has important implications for the Indian subcontinent as well as other developing countries. However, such regimens of shorter duration trastuzumab therapy like FinHer, offered in view of economic constraints, may not be able to achieve globally comparable cure rates in early breast cancer especially with high-risk women with more than 3 lymph node positive. Methods and Material: Outcome of 21 patients with HER2 positive breast cancer was treated with short course trastuzumab combination chemotherapy in the adjuvant setting was studied. Results: Out of 21 patients 15 are alive and disease free with a follow up of up to 73 months (median follow up 42 months).


How to cite this article:
Hingmire SS, Sambhus MB, Kelkar DS, Joshi S, Parikh PM, Bharath R. Efficacy and safety of short course adjuvant trastuzumab combination chemotherapy in breast cancer.South Asian J Cancer 2017;6:47-50


How to cite this URL:
Hingmire SS, Sambhus MB, Kelkar DS, Joshi S, Parikh PM, Bharath R. Efficacy and safety of short course adjuvant trastuzumab combination chemotherapy in breast cancer. South Asian J Cancer [serial online] 2017 [cited 2017 Nov 25 ];6:47-50
Available from: http://journal.sajc.org/article.asp?issn=2278-330X;year=2017;volume=6;issue=2;spage=47;epage=50;aulast=Hingmire;type=0