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Year : 2019  |  Volume : 8  |  Issue : 1  |  Page : 69-71

Multimodality treatment of head-and-neck soft-tissue sarcomas and short-term outcomes: Analysis from sarcoma medical oncology clinic

1 Department of Medical Oncology, IRCH, AIIMS, New Delhi, India
2 Department of Radiation Oncology, Lok Nayak Hospital, New Delhi, India
3 Department of Surgical Oncology, IRCH, AIIMS, New Delhi, India
4 Department of Pathology, AIIMS, New Delhi, India
5 Department of Radiodiagnosis, IRCH, AIIMS, New Delhi, India
6 Department of Radiation Oncology, IRCH, AIIMS, New Delhi, India
7 Department of Oncoanaesthesia, IRCH, AIIMS, New Delhi, India

Correspondence Address:
Dr. Sameer Rastogi
Department of Medical Oncology, IRCH, AIIMS, New Delhi
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/sajc.sajc_229_18

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Background: Head-and-neck soft-tissue sarcomas (HNSTS) are extremely rare and lack definite guidelines. Methods: We retrospectively analyzed consecutive adult patients with HNSTS who presented to our sarcoma medical oncology clinic from January 2016 to October 2017. Results: There were a total of 30 patients. Unresectable localized disease was seen in 13 (43%) patients, metastatic disease 10 (34%) patients, while resectable disease in 7 (23%) patients only. Among unresectable localized disease, 3 (25%) patients could be converted to resectable disease after neoadjuvant therapy. Median follow period was 11 months. Progression-free survival was 19 months in patients with resectable disease and 6 months in patients with the unresectable/metastatic disease. Median OS was not reached. Conclusion: Unresectable HNSTS has a poor outcome. Neoadjuvant therapy can be tried in selected cases for achieving respectability or for vital organ preservation until robust data are available. A multidisciplinary approach for local control is crucial in managing unresectable HNSTS.

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