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ORIGINAL ARTICLE
Year : 2018  |  Volume : 7  |  Issue : 2  |  Page : 127-131

Practical consensus recommendations on management of triple-negative metastatic breast cancer


1 Department of Medical Oncology, Max Hospital, New Delhi, India
2 Dept of Medical Oncology, Bombay Hospital, Mumbai, Maharashtra, India
3 Department of Radiation Oncology, MAMC, New Delhi, India
4 Department of Radiation Oncology, Safdarjung Hospital, New Delhi, India
5 Department of Medical Oncology, Metro Cancer Center, New Delhi, India
6 Department of Radiation Oncology, GMC, Jammu and Kashmir, India
7 Department of Surgical Oncology, Indraprastha Apollo Hospital, New Delhi, India
8 Department of Surgical Oncology, Manipal Super Specialty Hospital, Gurugram, Haryana, India
9 Department of Oncology, Shalby Cancer and Research Institute, Mumbai, Maharashtra, India
10 Department of Medical Oncology, Sir Ganga Ram Hospital, New Delhi, India

Correspondence Address:
Dr. R Rangarao
Department of Medical Oncology, Max Hospital, New Delhi
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/sajc.sajc_118_18

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Patients with breast cancer along with metastatic estrogen and progesterone receptor (ER/PR)- and human epidermal growth factor receptor 2 (HER2)-negative tumors are referred to as having metastatic triple-negative breast cancer (mTNBC) disease. Resistance to current standard therapies such as anthracyclines or taxanes limits the available options for previously treated patients with metastatic TNBC to a small number of non-cross-resistant regimens, and there is currently no preferred standard chemotherapy. Clinical experience suggests that many women with triple-negative metastatic breast cancer (MBC) relapse quickly. Expert oncologist discussed about new chemotherapeutic strategies and agents used in treatment of mTNBC and the expert group used data from published literature, practical experience and opinion of a large group of academic oncologists to arrive at this practical consensus recommendations for the benefit of community oncologists.


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