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Year : 2017  |  Volume : 6  |  Issue : 3  |  Page : 93-98

Human papillomavirus in head and neck cancer in India: Current status and consensus recommendations


1 Department of Radiation Oncology, Tata Memorial Centre, Mumbai, Maharashtra, India
2 Department of Oncopathology, Metropolis Healthcare Ltd., Mumbai, Maharashtra, India
3 Department of Head and Neck Surgery, Tata Memorial Centre, Mumbai, Maharashtra, India
4 Department of Surgical Oncology, Cancer Institute (WIA), Chennai, Tamil Nadu, India
5 Department of Radiation Oncology, Tata Medical Centre, Kolkata, West Bengal, India
6 Teni Lab, Advanced Centre for Treatment, Research and Education in Cancer, Mumbai, Maharashtra, India
7 Department of Radiation Oncology, KDAH, Mumbai, Maharashtra, India
8 Department of Pathology, Tata Memorial Centre, Mumbai, Maharashtra, India
9 Department of Medical Oncology, Avinash Cancer Clinic, Pune, Maharashtra, India
10 Department of Medical Oncology, Cytecare Cancer Hospital, Bengaluru, Karnataka, India
11 Department of Medical Oncology, Yashoda Cancer Institute, Somajiguda, Hyderabad, Telangana, India
12 Department of Medical Oncology, Indraprastha Apollo Hospitals, New Delhi, India
13 Department of Surgical Oncology, Mazumdar-Shaw Cancer Center, Bengaluru, Karnataka, India
14 Department of Medical Oncology, Tata Memorial Centre, Mumbai, Maharashtra, India
15 Department of Medical Oncology, Asian Institute of Oncology, Mumbai, Maharashtra, India

Correspondence Address:
Vedang Murthy
Department of Radiation Oncology, Tata Memorial Centre, Mumbai, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/sajc.sajc_96_17

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Human papillomavirus (HPV) associated head and neck squamous cell cancers (HNSCC) have become increasingly common in the West, but the same cannot be said about India. These cancers have a different biology and confer a better prognosis, however, its current role in the management of patients in India is not clearly defined. At the 35th Indian Cooperative Oncology Network conference held in September 2016, a panel of radiation, surgical and medical oncologists, pathologists, and basic scientists from across the country having experience in clinical research with respect to HPV in HNSCC reviewed the available literature from India. All the ideas and facts were thereafter collated in this report. Various topics of controversy in dealing with the diagnosis and management of HPV-associated HNSCC have been highlighted in this report in context to the Indian scenario. Furthermore, the prevalence of the same and its association with tobacco and high-risk sexual behavior has been touched on. Conclusively, a set of recommendations has been proposed by the panel to guide the practicing oncologists of the country while dealing with HPV-associated HNSCC.


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